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Use of microorganisms and enzymes in production

Use of microorganisms and enzymes in production

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Covestro is expanding its competencies in industrial biotechnology. The plastics manufacturer intends to make increasing use of microorganisms and enzymes to make its products and processes even more sustainable. In particular, new recycling processes based on biotechnology are also to be developed. To this end, the biotechnology competence center, which has been in operation for four years, has now been expanded to include a publicly funded research group. At the same time, Covestro is making progress in its efforts to produce the important chemical aniline entirely from plants for the first time with the help of microorganisms.

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Dr. Gernot Jäger (pictured on the left) heads the Biotechnology Competence Center at Covestro, which was established four years ago. The new junior research group for enzyme catalysis funded by the German Federal Ministry of Education and Research is headed by Dr. Lukas Reisky.

“Biotechnology has enormous potential to produce plastics in a more environmentally friendly and efficient way,” says Dr. Markus Steilemann, CEO of Covestro. “As an innovation-oriented company, we want to expand our capabilities in this area. In particular, we expect this to provide further stimulus for the circular economy, to which we are completely gearing our company.”

Recycling with enzymes
In order to better tap the potential of industrial (“white”) biotechnology for plastics production, the junior research group enzyme catalysis, or NEnzy for short, has now been established at Covestro. It will receive a total of 2.5 million Euros in funding from the German Federal Ministry of Education and Research for five years and is cooperating closely with RWTH Aachen University in Germany.

The new group is working to recycle end-of-life products and plastic waste through enzymatic recycling. The researchers also want to use enzymes to treat wastewater in plastics production. Another focus is the targeted and complete decomposition of used plastic in nature.

New laboratory
The experts now also have more space and even better equipment – in a new laboratory that Covestro has built at its headquarters in Leverkusen. Here, biotechnological processes can be represented in a particularly realistic way in a wide range of sizes, from one milliliter to soon 100 liters of reaction volume.

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Dr. Lena Schaffert in the new laboratory of the Competence Center for Biotechnology

“We are taking nature as our model, which has created sensational processes and has practiced closed-loop recycling for millions of years,” says Dr. Gernot Jäger, who heads Covestro's Biotechnology Competence Center. “With the help of enzymes and microorganisms, we can efficiently use alternative raw materials and thus replace fossil resources. At the same time, unwanted byproducts can be avoided or at least reduced significantly.”

Chemicals from plants
Specifically, Covestro is already using biotechnology to research and develop new ways to sustainably produce aniline. This basic chemical plays an important role in plastics production worldwide. Until now, it has been obtained almost exclusively from fossil raw materials such as petroleum, which releases CO2. Covestro needs aniline to produce a precursor (MDI) that is used to make insulating foam for buildings and refrigeration equipment.

Together with partners from industry and science, Covestro has developed a pioneering process to produce aniline from plant-based raw materials such as straw or sugar beet plants in an environmentally compatible way using microorganisms. Fully biobased aniline has already been obtained in this way and successfully processed into test products. Now the process, which has already won several awards, is to be further developed on a larger scale. The project is funded with public funds from the German Federal Ministry of Food and Agriculture.

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At the Biotechnology Competence Center, experts such as Muhammed Demiral and Melanie Prinz conduct research into producing the basic chemical aniline from plants, among other things

Another precursor for coatings and adhesives (HMDA) can already be produced on a larger scale from plants and with the aid of biotechnology. Covestro and the U.S.-based biotech company Genomatica have succeeded in doing this through a partnership.

In biotechnology, there are several major areas that are identified by colors.

White or industrial biotechnology is used in industrial production processes, especially in the chemical industry.

Green biotechnology helps in agriculture, for example, to make plants more resistant to climate change.

Red biotechnology advances medicine – for example, to produce vaccines like those used to protect against Corona.

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